Falla hepática aguda sobre crónica (ACLF), síndrome subdiagnosticado con alta mortalidad / Acute-on-chronic liver failure (ACLF), an underdiagnosed syndrome with high mortality
Rev. Hosp. Clin. Univ. Chile
; 32(1): 29-37, 2021. tab, graf
Article
em Es
| LILACS
| ID: biblio-1353347
Biblioteca responsável:
CL36.1
ABSTRACT
Acute on chronic liver failure is an increasingly recognized syndrome characterized by acute decompensation of chronic liver disease associated with organ failure and high short-term mortality. ACLF is frequent, affecting between 24 and 40% of patients admitted for complications of cirrhosis. Sepsis, active alcoholism, and relapse of chronic viral hepatitis are the most frequent precipitating factors. However, in up to 40%50% of the cases of ACLF have no identifiable trigger. The stage of severity of Acute on chronic liver failure is very important because it allows us to stratify patients according to their prognosis, evaluate therapeutic response, determine transplant urgency, deciding intensive care unit admission, and also have a basis on which to decide therapeutic futility. (AU)
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Insuficiência Hepática Crônica Agudizada
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Es
Revista:
Rev. Hosp. Clin. Univ. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Chile