Loss to follow-up and opportunities for reengagement in HIV care in rural Mozambique. A prospective cohort study
Medicine journal
; 99(6): 1-10, 20200515. graf, tab
Artigo
em Inglês
| RDSM
| ID: biblio-1358123
Biblioteca responsável:
MZ1.1
ABSTRACT
Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique. Newly diagnosed HIV-positive adults were consecutively recruited in the Manhiça District. Patients LTFU within 12 months after HIV diagnosis were visited at home from June 2015 to July 2016 and interviewed for ascertainment of outcomes and reasons for LTFU. Factors associated with reengagement in care within 90 days after the home visit were analyzed by Cox proportional hazards model. Among 1122 newly HIV-diagnosed adults, 691 (61.6%) were identified as LTFU. Of those, 557 (80.6%) were approached at their homes and 321 (57.6%) found at home. Over 50% had died or migrated, 10% had been misclassified as LTFU, and 252 (78.5%) were interviewed. Following the visit, 79 (31.3%) reengaged in care. Having registered in care and a shorter time between LTFU and visit were associated with reengagement in multivariate analyses adjusted hazards ratio of 3.54 [95% confidence interval (CI) 1.81 6.92; P<.001] and 0.93 (95% CI 0.871.00; P=.045), respectively. The most frequently reported barriers were the lack of trust in the HIV-diagnosis, the perception of being in good health, and fear of being badly treated by health personnel and differed by type of LTFU. Estimates of LTFU in rural areas of sub-Saharan Africa are likely to be overestimated in the absence of active tracing strategies. Home visits are resource-intensive but useful strategies for reengagement for at least one-third of LTFU patients when applied in the context of differentiated care for those LTFU individuals who had already enrolled in HIV care at some point.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Moçambique
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Base de dados:
RDSM
Assunto principal:
Infecções por HIV
/
Perda de Seguimento
/
Cooperação e Adesão ao Tratamento
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
África
Idioma:
Inglês
Revista:
Medicine journal
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Centers for Disease Control and Prevention/US
/
Centro de Investigação em Saude de Manhiça/MZ
/
ISGlobal, Barcelona Institute for Global Health, Hospital Clínic Universitat de Barcelona/ES