Risk of premature coronary atherosclerosis in patients with nonalcoholic fatty liver disease
Rev. Assoc. Med. Bras. (1992, Impr.)
; 68(10): 1428-1433, Oct. 2022. tab
Artigo
em Inglês
|
LILACS-Express
| LILACS
| ID: biblio-1406566
Biblioteca responsável:
BR1.1
ABSTRACT
SUMMARY OBJECTIVE:
In the current literature, there are few studies investigating the relationship between premature coronary atherosclerosis and nonalcoholic fatty liver disease. We aimed to evaluate the relationship between nonalcoholic fatty liver disease and premature coronary atherosclerosis.METHODS:
In this cross-sectional study, female patients aged <55 years and male patients aged <50 years were enrolled. Both male and female patients underwent coronary angiography and abdomen ultrasonography between 2014 and 2019. A stepwise binary logistic regression analysis was carried out to evaluate the independent variables related to premature coronary atherosclerosis and nonalcoholic fatty liver disease. A p-value<0.05 was considered statistically significant.RESULTS:
nonalcoholic fatty liver disease was present in 44% of patients (n=377). Notably, 62% of the patients were female and the mean age was 44.5 (39-49) years. In a multivariate analysis, nonalcoholic fatty liver disease was shown to be an independent risk factor of premature coronary atherosclerosis (OR 1.438; 95%CI, 1.050-1.969; p=0.024).CONCLUSIONS:
The presence of nonalcoholic fatty liver disease is an important independent risk factor for the development of premature coronary atherosclerosis.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Fatores de risco
Idioma:
Inglês
Revista:
Rev. Assoc. Med. Bras. (1992, Impr.)
Assunto da revista:
EducaÆo em Sa£de
/
GestÆo do Conhecimento para a Pesquisa em Sa£de
/
Medicina
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Turquia
Instituição/País de afiliação:
Edirne State Hospital/TR
/
Trakya University/TR