Discordant retention of HIV-infected mothers and children: Evidence for a family-based approach from Southern Mozambique
Medicine (Baltimore)
; 99(32): 1-8, 7 Ago. 2020. Tab, Ilus
Artigo
em Inglês
| RDSM
| ID: biblio-1525661
Biblioteca responsável:
MZ1.1
ABSTRACT
It is often assumed that children and their caregivers either stay in care together or discontinue together, but data is lacking on caregiverchild retention concordance. We sought to describe the pattern of care among a cohort of human immunodeficiency virus (HIV) infected children and mothers enrolled in care at the Manhiça District Hospital (MDH). This was a retrospective review of routine HIV clinical data collected under a larger prospective HIV cohort study at MDH. Children enrolling HIV care from January 2013 to November 2016 were identified and matched to their mother's HIV clinical data. Retention in care for mothers and children was assessed at 24 months after the child's enrolment. Multinomial logistic regression was performed to evaluate variables associated with retention discordance. For the 351 motherchild pairs included in the study, only 39% of mothers had concordant care status at baseline (23% already active in care, 16% initiated care concurrently with their children). At 24-months follow up, a total of 108 (31%) motherchild pairs were concordantly retained in care, 88 (26%) pairs were concordantly lost to follow up (LTFU), and 149 (43%) had discordant retention. Pairs with concurrent registration had a higher probability of being concordantly retained in care. Children who presented with advanced clinical or immunological stage had increased probability of being concordantly LTFU. High rates of LTFU as well as high proportions of discordant retention among motherchild pairs were found. Prioritization of a family-based care model that has the potential to improve retention for children and caregivers is recommended. Abbreviations aRRR = adjusted relative risk ratio (RRR) coefficient, ART = antiretroviral therapy, CASG = community antiretroviral therapy support groups, CDC = Center for Disease Control, CISM = Centro de Investigação em Saude de Manhiça, DSDM = differentiated service delivery models, EID = Early Infant Diagnosis, ePTS = electronic HIV patient tracking systems, HDSS = Health and Demographic Surveillance System, HIV = human immunodeficiency virus, IeDEA-SA = International Epidemiological Databases to Evaluate AIDS in Southern Africa, LTFU = lost to follow up, MDH = Manhiça District Hospital, MoH = Mozambique Ministry of Health, PMTCT = prevention of mother to child transmission, UNAIDS = The Joint United Nations Programme on HIV and AIDS, WHO = world health organization.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Moçambique
Base de dados:
RDSM
Assunto principal:
Infecções por HIV
Limite:
Criança, pré-escolar
/
Humanos
/
Recém-Nascido
País/Região como assunto:
África
Idioma:
Inglês
Revista:
Medicine (Baltimore)
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Centro de Investigação em Saúde de Manhiça/MZ
/
Instituto de Saúde de Global de Barcelona/ES