Alternative approaches for creating a wealth index: the case of Mozambique
BMJ glob. health
; 8(8): 2-16, ago. 2023. tab, graf
Artigo
em Inglês
| RDSM
| ID: biblio-1531585
Biblioteca responsável:
MZ1.1
ABSTRACT
Background Residual malaria transmission is the result of adaptive mosquito behavior that allows malaria vectors to thrive and sustain transmission in the presence of good access to bed nets or insecticide residual spraying. These behaviors include crepuscular and outdoor feeding as well as intermittent feeding upon livestock. Ivermectin is a broadly used antiparasitic drug that kills mosquitoes feeding on a treated subject for a dose-dependent period. Mass drug administration with ivermectin has been proposed as a complementary strategy to reduce malaria transmission. Methods A cluster randomized, parallel arm, superiority trial conducted in two settings with distinct eco-epidemio logical conditions in East and Southern Africa. There will be three groups human intervention, consisting of a dose of ivermectin (400 mcg/kg) administered monthly for 3 months to all the eligible population in the cluster (>15 kg, nonpregnant and no medical contraindication); human and livestock intervention, consisting human treatment as above plus treatment of livestock in the area with a single dose of injectable ivermectin (200 mcg/kg) monthly for 3 months; and controls, consisting of a dose of albendazole (400 mg) monthly for 3 months. The main outcome measure will be malaria incidence in a cohort of children under fve living in the core of each cluster followed prospectively with monthly RDTs Discussion The second site for the implementation of this protocol has changed from Tanzania to Kenya. This sum mary presents the Mozambique-specifc protocol while the updated master protocol and the adapted Kenya-specifc
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Moçambique
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
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Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
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Malária
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Doenças Negligenciadas
Base de dados:
RDSM
Assunto principal:
Anafilaxia Cutânea Passiva
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Saúde Única
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Malária
Limite:
Animais
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Feminino
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Humanos
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Masculino
País/Região como assunto:
África
Idioma:
Inglês
Revista:
BMJ glob. health
Ano de publicação:
2023
Tipo de documento:
Artigo
Instituição/País de afiliação:
1Department of Statistics, Virginia Tech/US
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4ISGlobal, Barcelona Institute for Global Health/SZ
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4ISGlobal, Barcelona Institute for Global Health, Barcelona/SZ
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5University Hospital of Bern, Inselspital/SZ
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5University Hospital of Bern,/SZ
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ISGlobal/AG
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ISGlobal/ES
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Network Systems Science and Advanced Computing Division, Biocomplexity Institute, University of Virginia/US