Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso / Differential diagnosis of bone marrow and lung granulomas: Report of one case
Rev. méd. Chile
; 145(5): 657-661, mayo 2017. ilus
Article
em Es
| LILACS
| ID: biblio-902523
Biblioteca responsável:
CL1.1
ABSTRACT
The differential diagnosis of pulmonary tuberculosis and lymphoma with pulmonary infiltration is very difficult, given their similar clinical characteristics. We report a 59 year old female with weight loss, fever, dyspnea and cough of several months of duration. She had a cavitated mass in lung imaging. A positive conventional PCR lead to the diagnosis of tuberculosis, but she had negative smears and cultures for Mycobacterium tuberculosis. The patient did not respond to treatment and her clinical condition worsened. A peripheral lymph node biopsy confirmed the presence of a diffuse large B cell non-Hodgkin lymphoma. Bone marrow pathology showed non caseating granulomas, again with negative microbiological tests for M. tuberculosis. Findings in the bone marrow were interpreted as a secondary sarcoid reaction to cancer and PCR results as a false positive. The lymphoma was treated, achieving complete remission. This case highlights the importance of the differential diagnosis between these two entities.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Tuberculose Pulmonar
/
Linfoma não Hodgkin
/
Neoplasias Pulmonares
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Chile