World Allergy Organization-McMaster University Guidelines for allergic disease prevention (GLAD-P): vitamin D
World Allergy Organ. J
; 9(1)2016. tab
Artigo
em Inglês
| BIGG - guias GRADE
| ID: biblio-916665
Biblioteca responsável:
BR1.1
ABSTRACT
BACKGROUND:
The prevalence of allergic diseases is approximately 10 % in infants whose parents and siblings do not have allergic diseases and 20-30 % in those with an allergic first-degree relative. Vitamin D is involved in the regulation of the immune system and it may play a role in the development, severity and course of asthma and other allergic diseases.OBJECTIVE:
The World Allergy Organization (WAO) convened a guideline panel to develop evidence-based recommendations addressing the use of vitamin D in primary prevention of allergic diseases.METHODS:
Our WAO guideline panel identified the most relevant clinical questions and performed a systematic review of randomized controlled trials and non-randomized studies (NRS), specifically cohort and case-control studies, of vitamin D supplementation for the prevention of allergic diseases. We also reviewed the evidence about values and preferences, and resource requirements (up to January 2015, with an update on January 30, 2016). We followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to develop recommendations.RESULTS:
Having reviewed the currently available evidence, the WAO guideline panel found no support for the hypothesis that vitamin D supplementation reduces the risk of developing allergic diseases in children. The WAO guideline panel suggest not using vitamin D in pregnant women, breastfeeding mothers, or healthy term infants as a means of preventing the development of allergic diseases. This recommendation does not apply to those mothers and infants who have other indications for prophylactic or therapeutic use of vitamin D. The panel's recommendations are conditional and supported by very low certainty evidence.CONCLUSIONS:
WAO recommendations about vitamin D supplementation for the prevention of allergic diseases support parents, clinicians and other health care professionals in their decisions whether or not to use vitamin D in preventing allergic diseases in healthy, term infants.(AU)
Texto completo:
Disponível
Coleções:
Bases de dados temática
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
/
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Objetivo 9: Redução de doenças não transmissíveis
/
Objetivo 10: Doenças transmissíveis
/
Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
Base de dados:
BIGG - guias GRADE
Assunto principal:
Vitamina D
/
Hipersensibilidade
Tipo de estudo:
Ensaio clínico controlado
/
Guia de prática clínica
/
Estudo observacional
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Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
World Allergy Organ. J
Ano de publicação:
2016
Tipo de documento:
Artigo
Instituição/País de afiliação:
Aga Khan University Hospital/KE
/
Charité Klinik für Pädiatrie/DE
/
Chongqing Medical University/CN
/
Food Allergy Research & Education/US
/
Hospital Infantil Universitario Niño Jesus/ES
/
Icahn School of Medicine at Mount Sinai/US
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McMaster University Health Sciences Centre/CA
/
McMaster University/CA
/
Nippon Medical School/JP
/
Pediatric Hospital Bambino Gesù/IT