Long-term survival rates in young patients with thyroid carcinoma
Arch. otolaryngol. head neck surg
; 129(7): 746-749, 2003.
Artigo
em Inglês
| Coleciona SUS
| ID: biblio-944152
Biblioteca responsável:
BR440.1
Localização: BR440.1
ABSTRACT
Thyroid carcinoma in patients younger than 18 years is rare. It is associated with a greater risk of metastases. However, the prognosis for these patients is better when compared with that of adults.To present the experience of a single institution in the treatment of patients with thyroid carcinoma during childhood and adolescence.Thirty-eight patients, ranging in age from 4 to 18 years, were diagnosed as having thyroid carcinoma. Pathologic types of carcinoma included 29 papillary, 4 follicular, 1 Hürthle cell, and 4 medullary cases. Hypocalcemia was the main complication, being transitory in 9 patients (24%) and permanent in 6 patients (16%). Vocal cord palsy occurred in 2 patients (5%). Two patients (5%) had a surgical site infection. After a mean follow-up of 9.5 years (range, 1-40 years), 28 patients (74%) were alive and had no evidence of disease, 3 (8%) were alive and had recurrent disease, 4 (11%) died (2 of the disease and 2 of non-cancer-related causes), and 3 (8%) were lost to follow-up. The survival rates at 10 years for the patients with papillary, follicular, and medullary carcinoma were 93%, 100%, and 50%, respectively. Thyroid carcinoma in patients younger than 18 years has a good prognosis even in the presence of neck or distant metastasis. Total thyroidectomy, associated with adjuvant radioactive iodine therapy and thyroidal suppression or not, is effective in patients with a well-differentiated thyroid carcinoma.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
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Brasil
Base de dados:
Coleciona SUS
Assunto principal:
Glândula Tireoide
/
Carcinoma
/
Sobreviventes
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Arch. otolaryngol. head neck surg
Ano de publicação:
2003
Tipo de documento:
Artigo