Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016
Intensive care med
; 43(3)Mar. 2017.
Artigo
em Inglês
| BIGG - guias GRADE
| ID: biblio-948600
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVE:
To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock 2012".DESIGN:
A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict-of-interest (COI) policy wasdeveloped at the onset of the process and enforced throughout. A stand-alone meeting was held for all panel members in December 2015. Teleconferences and electronic-based discussion among subgroupsand among the entire committee served as an integral part of the development.METHODS:
The panel consisted of five sections hemodynamics, infection, adjunctive therapies, metabolic, and ventilation. Population, intervention, comparison, and outcomes (PICO) questions were reviewed and updated as needed, and evidence profiles were generated. Each subgroup generated a list of questions, searched for best available evidence, and then followed the principles of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the quality of evidence from high to very low, and to formulate recommendations as strong or weak, or best practice statement when applicable.RESULTS:
The Surviving Sepsis Guideline panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock. Overall, 32 were strong recommendations, 39 were weak recommendations, and 18 were best-practice statements. No recommendation was provided for four questions.CONCLUSIONS:
Substantial agreement exists among a large cohort of international experts regarding many strong recommendations for the best care of patients with sepsis. Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality.(AU)
Texto completo:
Disponível
Coleções:
Bases de dados temática
Base de dados:
BIGG - guias GRADE
Assunto principal:
Choque Séptico
/
Sepse
Tipo de estudo:
Guia de prática clínica
/
Estudo prognóstico
/
Pesquisa qualitativa
Idioma:
Inglês
Revista:
Intensive care med
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
Brown University School of Medicine/US
/
CHIREC Hospitals/BE
/
California Pacific Medical Center/US
/
Centro Hospitalar de Lisboa Central/PT
/
Christiana Care Health Services/US
/
Cooper Health System/US
/
Emory University Hospital/US
/
Erasmé University Hospital/BE
/
Federal University of Sao Paulo/BR
/
Fujita Health University/JP