Ointment of Ximenes americana promotes acceleration of wound healing in rats
Acta cir. bras
; 34(3): e201900307, 2019. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-989071
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Purpose:
To evaluate the healing potential of the Ximenia americana hydroalcoholic extract in 10% cream in excisional wound models in rats.Methods:
Sixty male adults Wistar rats were submitted to skin and subcutaneous tissue surgery in the right and left thoracic regions, divided into three experimental groups Standard submitted to treatment with only the base vehicle, Treated wounds treated with hydroalcoholic extract of X. americana applied on 10%, Lanette base and Control, untreated wounds. The treatment was performed daily and the wounds evaluated microscopically by the quantification of fibroblasts, collagen fibers and blood vessels.Results:
The histomorphometric analysis showed a significant increase in the number of fibroblasts, collagen fibers and blood vessels in the treated group.Conclusion:
The topical action of the cream based on Ximenia americana shows angiogenic effects and improves the replacement of collagen, suggesting its use for the development of herbal remedy in the treatment of cutaneous wound healing.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Cicatrização
/
Extratos Vegetais
/
Olacaceae
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
UFRPE/BR
/
UNIFESP/BR
/
Universidade Federal Rural de Pernambuco/BR
/
Universidade Federal de São Paulo/BR