Accurate diagnose and management of advanced nasal type extranodal nk/t cell lymphoma. a case report
Case reports (Universidad Nacional de Colombia. En línea)
; 3(1): 42-48, Jan.-June 2017. tab, graf
Artigo
em Inglês
| LILACS, COLNAL
| ID: biblio-989548
Biblioteca responsável:
CO136.1
ABSTRACT
ABSTRACT Extranodal natural killer (NK)/T-cell lymphoma, nasal type, is a rare entity in otorhinolaryngology. Its management requires skilled physicians in order to suspect this disease and making a proper diagnosis at early stages. This paper reports the case of a 31-year-old male patient, with one month of nasal obstruction, recurrent sinusitis, palatal ulceration and a necrotizing lesion. Histopathology reported lymphoid infiltrate polymorph angiocentric growth pattern and extensive areas of necrosis. Immunohistochemistry confirmed the phenotype for T/NK cells positive CD3, BCL2, CD4 and CD56. IgG for Epstein-Barr virus was also positive. The initial staging was T4, N1, M0, Eastern Cooperative Oncology Group (ECOG) scale was 1, with intermediate risk, and low International Prognostic Index (IPI); based on this results, the patient was referred to oncology to initiate treatment. After a ten-month follow-up, the patient's condition improved, with complete remission of nasal and palate injuries; no relapse has occurred to date. This case is a clear example of the importance of early diagnostic through multiple biopsies in order to establish a specific treatment to decrease complication rates and improve prognosis.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
COLNAL
/
LILACS
Assunto principal:
Linfoma Extranodal de Células T-NK
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Case reports (Universidad Nacional de Colombia. En línea)
Assunto da revista:
Cincias da Sa£de
/
Medicina
/
Relatos de Casos
Ano de publicação:
2017
Tipo de documento:
Artigo
País de afiliação:
Colômbia
Instituição/País de afiliação:
Universidad Nacional de Colombia/CO
/
Universidad de La Sabana/CO