Osteomalacia por tumor secretor de FGF-23. / [Ostemalacia due to a tumor secreting FGF-23].
Medicina (B Aires)
; 73(1): 43-6, 2013.
Artigo
em Espanhol
| BINACIS
| ID: bin-133223
ABSTRACT
A case of oncogenic osteomalacia in a 50-year-old male is here presented. He suffered severe bone pain and marked muscular weakness of 4 years duration. There were several vertebral deformities in the thoracic spine, bilateral fractures of the iliopubic branches, another fracture in the left ischiopubic branch, and a Loosers zone in the right proximal tibia. An octreotide-Tc scan allowed to identify a small tumor in the posterior aspect of the right knee. It was surgically removed. Microscopically, it was a phosphaturic mesenchymal tumor-mixed connective tissue (PMT-MCT). Expression of FGF-23 was documented by immune-peroxidase staining. There was rapid improvement, with consolidation of the pelvic fractures and the tibial pseudo-fracture. The laboratory values returned to normal.
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Coleções:
Bases de dados nacionais
/
Argentina
Base de dados:
BINACIS
Assunto principal:
Fatores de Crescimento de Fibroblastos
/
Mesenquimoma
/
Neoplasias de Tecido Conjuntivo
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
Idioma:
Espanhol
Revista:
Medicina (B Aires)
Ano de publicação:
2013
Tipo de documento:
Artigo