Sensibilidad del equipo Cobas AmpliScreenÔäó HIV-1 Test, v1.5, para la detección de HIV-1. / [Sensitivity of the COBAS AmpliScreenÔäó HIV-1 test v1.5 for HIV-1 detection].

ABSTRACT

The introduction of nucleic acid amplification techniques (NAT) in blood banks was intended to reduce the residual risk of transfusion-transmitted infections. Co-circulation of a great diversity of HIV-1 variants in Argentina portrays the need to assess the sensitivity of serological and molecular assays available for their detection. In this study, we evaluated the sensitivity of the COBAS AmpliScreen HIV-1 Test, version 1.5 (Roche) for the detection of HIV-1 RNA in plasma samples of infected individuals from Argentina. The results of this study reveal that this technique has high sensitivity for the detection of HIV-1 RNA under assay conditions using mini-pool testing, pools  50 RNA copies per ml achieved  92