El tiempo y el pH de desaparición de la pirosis provocada por la perfusión ácida de esófago sería un indicador de hiperalgesia. / The time and pH at the moment of disappearance of pyrosis induced by of esophagus acid perfusion is an indicator of hyperalgesiaO.

ABSTRACT

OBJECTIVES: 1) Describe and compare evolutionary features of the pyrosis symptom with a positive acid perfusion test in the entire study population, and divided by sex. 2) Describe the results of different tests according to sex (standard acid clearance, number of reflux episodes in a short testing period, period of time until the appearance of pyrosis during acid perfusion, period of time until its disappearance, and esophagus pH at the time). 3) Compare differences between control and patient cases regarding standard clearance and reflux episodes. 4) Establish a multivariance correlation between the results of the tests according to sex and historical data, looking for one or more regulating factors. 5) Establish the same descriptive and comparative assessments in both subgroups, with and without hiatal hernia (HH). STUDY POPULATION 15 healthy subjects, 9 men and 6 women (control), and 50 patients with pyrosis, 23 men and 27 women, over 18 years old, with or without HH, matched for age and sex (p = NS), and consecutive. MATERIAL AND METHODS: Clinical data records, esophagogastroendoscopy with at least three biopsy samples, number of reflux episodes within 30 minutes, standard acid clearance, measurement of perfusion time, time it takes pyrosis to disappear, and esophagus pH at the time. This is a prospective, descriptive, comparative, experimental, longitudinal, single-blind study with control subjects. RESULTS: Eighty-two percent (82