Cardiovascular reactivity and neurogenic tone in hypertension derived from renal artery stenosis and contralateral nephrectomy in the rat.
Acta Physiol Lat Am
; 27(5): 231-8, 1977.
Artigo
em Inglês
| BINACIS
| ID: bin-47722
Biblioteca responsável:
AR1.1
ABSTRACT
In the current study a) cardiovascular reactivity (CR) to norepinephrine (NE) and b) the effect of a ganglionic blocker (pentolinium, P) during the early (2nd week) and a later period (10th week) of hypertension elicited by unilateral renal ischemia and contralateral nephrectomy in the rat have been described. Neither the threshold doses nor the dose-pressor response curves have shown a greater reactivity of the cardiovascular system to NE in this type of hypertension. An increase in the activity of the nervous system apparently contributes to hypertension in the early period but would disappear when the one-kidney renovascular hypertension is chronically established; in both phases some other still undefined factor/s are present for fuller development of high arterial pressure.
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Argentina
Base de dados:
BINACIS
Idioma:
Inglês
/
Espanhol
Revista:
Acta Physiol Lat Am
/
Acta physiol. latinoam
Ano de publicação:
1977
Tipo de documento:
Artigo