Mecanismo inhibidor COX-2 y COX-3 en el daño gastrointestinal inducido por AINE en ratas / Mechanism of inhibition OF COX-2 and COX-3 in gastrointestinal damage induced by NSAID in rats
Acta gastroenterol. latinoam
; 33(4): 183-185, 2003. tab
Artigo
em Espanhol
| BINACIS
| ID: bin-4801
Biblioteca responsável:
BR1.1
ABSTRACT
In randomized groups of Wistar rats, the effect inhibitor of selective NASAID over the COX-1, COX-2 and COX-3 the synchronizes inhibition of COX-1 and COX-2, COX-1 and COX-3, COX-2 and COX-3, and COX-1, COX-2 and COX-3 were studied. The conclusions were that the selective inhibition of COX-1, COX-2 and COX-3 no given gastrointestinal damage; the synchronizes inhibition of COX-1 and COX-2 given preferential gastric damage; in contrast the inhibition of COX-2 and COX-3 given massive necrosis preferential in small intestine.(AU)
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Argentina
Base de dados:
BINACIS
Assunto principal:
Inibidores de Ciclo-Oxigenase
/
Trato Gastrointestinal
/
Isoenzimas
Limite:
Animais
Idioma:
Espanhol
Revista:
Acta gastroenterol. latinoam
Ano de publicação:
2003
Tipo de documento:
Artigo
Instituição/País de afiliação:
Universidad Nacional de Rosario/Argentina