Ictericia por metimazol. / [Jaundice caused by methimazole]
Acta gastroenterol. latinoam
; 21(2): 115-9, 1991.
Artigo
em Espanhol
| BINACIS
| ID: bin-51318
Biblioteca responsável:
AR40.1
ABSTRACT
Three female patients with cholestatic jaundice related to methimazole therapy are presented. The jaundice appeared after more or less 30 days of therapy. Markers for hepatitis A and B were negative in all. None of them had previous history of alcoholism or ingestion of potentially hepatotoxic drugs. Characteristically there was a marked elevation of alkaline phosphatase and gamma-glutamyltranspeptidase with only moderate increase of the aminotransferases. Liver biopsy performed in all showed intensive cholestasis with low degree of inflammatory reaction confined to the portal tracts. The three patients presented a prolonged duration of the liver injury in spite of the interruption of the drug lasting in one of them up to one year, but all ultimately resolved.
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Argentina
Base de dados:
BINACIS
Idioma:
Espanhol
Revista:
Acta gastroenterol. latinoam
Ano de publicação:
1991
Tipo de documento:
Artigo