Synthesis of glycal amides from amino acid esters by carbonylative coupling reaction
European J Org Chem, v. 2022, n. 30, e202200332, ago. 2022
Artigo
em Inglês
| Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP
| ID: bud-4473
Biblioteca responsável:
BR78.1
ABSTRACT
Glycal amides were prepared for the first time by reacting 2-iodo-D-glycals with L-amino acid esters via a Pd-catalyzed carbonylative cross-coupling reaction, by using Mo(CO)6 as the carbon monoxide source. Glycal amides were synthesized in moderate to good yields under our optimized conditions. In addition, the acetyl groups of the glucal amides could be readily removed to obtain the corresponding trihydroxy derivatives in good yields.
Texto completo:
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Coleções:
Bases de dados nacionais
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Brasil
Base de dados:
Sec. Est. Saúde SP
/
SESSP-IBPROD
Idioma:
Inglês
Revista:
European J Org Chem
Ano de publicação:
2022
Tipo de documento:
Artigo