Carbonylative negishi-type coupling of 2-Iodoglycals with alkyl and aryl halides
European J. Org. Chem.
; 2019(44): 7384-7388, 2019.
Artigo
em Inglês
| Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP
| ID: but-ib17307
Biblioteca responsável:
BR78.1
Localização: BR78.1
ABSTRACT
C-Glycosides are valuable organic compounds in the field of medicinal chemistry due to their ubiquity inside living systems and pronounced biological activity. Herein, we describe an approach to alkyl-ketones bearing glycal units via the Pd-catalyzed carbonylative coupling of 2-iodoglycals and alkyl and aryl halides. Examples bearing a variety of functional groups are presented as well as a mechanistic proposal for this transformation.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Brasil
Base de dados:
Sec. Est. Saúde SP
/
SESSP-IBPROD
Idioma:
Inglês
Revista:
European J. Org. Chem.
Ano de publicação:
2019
Tipo de documento:
Artigo