Severe anaphylactic reaction during the second infusion of infliximab in a patient with psoriatic arthritis
Allergol. immunopatol
; 33(5): 291-292, sept. 2005.
Artigo
em En
| IBECS
| ID: ibc-042142
Biblioteca responsável:
ES1.1
Localização: ES1.1 - BNCS
ABSTRACT
A 33-yer-old woman with no history of atopy, diagnosed of psoriatic arthritis, received 200 mg I.V. infliximab, with previous oral administration of loratadine and betamethasone, that was well tolerated. Two minutes after a second infusion two weeks later, with the same pretreatment, the patients suffer dyspnea, laryngeal spasm, generalized tremor, vomiting, hypotension, sinusal tachycardia, anxiety and hyposemia. She recovered in 45 minutes, after the administration of I.V. hydrocortisone, chloropyramine, adrenaline and oxigene. Several reports of infliximab-induced anaphylactic reactions have been published, especially in patients with Crohn's disease, that have been attributed to a type I (acute or delayed) hypersensitivity reaction mechanism
RESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Artrite Psoriásica
/
Hipersensibilidade a Drogas
/
Anafilaxia
/
Anticorpos Monoclonais
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Allergol. immunopatol
Ano de publicação:
2005
Tipo de documento:
Artigo
Instituição/País de afiliação:
Hospital de Especialidades Miguel Hidalgo/México