Cushing’s paraneoplastic syndrome as first manifestation of an adenocarcinoma of unknown origin

RESUMEN

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ABSTRACT

Small cell lung cancer is the most common cause ofparaneoplastic Cushing’s syndrome. The definitivetreatment consists in surgical removal of the tumour,which is not possible in most of these cases(they are often diagnosed at advanced stages), andtherefore it is frequently necessary adding the drugketoconazol.We hereby present the case of a patient diagnosedwith a metastatic carcinoma of unknown origin associatedwith two paraneoplastic syndromes aCushing’s syndrome and a sensitive-motor axonalneuropathy, a very uncommon association