May T1 diabetes mellitus protect from asthma?
Allergol. immunopatol
; 41(5): 288-291, sept.-oct. 2013. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-116397
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background:
Type 1 diabetes mellitus (T1DM) may be associated with allergy. It was previously reported that >20% of children with T1DM had allergic rhinitis (AR), but none was asthmatic. This finding was surprising as allergic rhinitis is frequently associated with asthma and asthma prevalence is about 10% of the general paediatric population. Thus, it was hypothesized that T1DM could protect from asthma.Objectives:
The aim of this preliminary study was to evaluate the pulmonary function and the response to bronchodilation testing in children, suffering from T1DM with associated AR, comparing them with a control group of children with AR alone.Methods:
Twenty children with T1DM and AR were compared with 59 children with AR alone; spirometry and bronchodilation testing were performed in all patients.Results:
There were no statistically significant differences in both at baseline and after bronchodilation testing about FVC, FEV1, and FEF2575 values. However, changes in post-bronchodilator values of FEF2575 (ΔFEF2575) were significantly higher in children with AR alone than in children with T1DM and AR (p = 0.04).Conclusions:
This preliminary study could sustain the hypothesis that T1DM in children suffering also from AR might exert a protective effect of preventing the possible evolution in asthma (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Asma
/
Rinite Alérgica Perene
/
Diabetes Mellitus Tipo 1
Tipo de estudo:
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Allergol. immunopatol
Ano de publicação:
2013
Tipo de documento:
Artigo
Instituição/País de afiliação:
IRCCS Azienda Ospedaliera Universitaria San Martino/Italy
/
Istituto Giannina Gaslini/Italy