Update in the management of ovarian and cervical carcinoma
Clin. transl. oncol. (Print)
; 9(7): 443-451, jul. 2007.
Artigo
em Inglês
| IBECS
| ID: ibc-123336
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Ovarian and cervical cancers are significant health problems. This article provides an update in selected management topics. Paclitaxel and platinum derivatives are the first-line treatment for patients with advanced disease. In selected patients, intraperitoneal chemotherapy has been associated with improved survival but the broad applicability of this strategy is limited by issues of toxicity and feasibility. Management of patients with recurrent disease is based on a number of factors and includes surgery in selected cases, platinum-based chemotherapy for patients with platinum-sensitive disease and other agents such as topotecan and pegylated liposomal formulation of doxorubicin for patients with platinum-resistant disease. In cervical cancer, the most significant issue/event is the demonstration of superior survival with topotecan and cisplatin compared to cisplatin alone. Finally, new agents such as epidermal growth factor receptor inhibitors and antiangiogenic agents are being currently tested in these settings (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Neoplasias Ovarianas
/
Carcinoma
/
Neoplasias do Colo do Útero
/
Cisplatino
/
Antineoplásicos
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2007
Tipo de documento:
Artigo
Instituição/País de afiliação:
Clínica Universitaria de Navarra/Spain
/
Hospital General Universitario Gregorio Marañón/Spain
/
Hospital Reina Sofía/Spain
/
Hospital Universitario Ramón y Cajal/Spain
/
Hospital Universitario de Guadalajara/Spain
/
Hospital Vall d´Hebrón/Spain
/
Hospital de Sant Pau/Spain
/
Instituto Catalán de Oncología/España
/
Instituto Valenciano de Oncología/Spain
/
University Hospital 12 Octubre/Spain