Lung adenocarcinoma in the era of targeted therapies: histological classification, sample priorization, and predictive biomarkers
Clin. transl. oncol. (Print)
; 15(7): 503-508, jul. 2013. ilus
Article
em En
| IBECS
| ID: ibc-127462
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
The arrival of targeted therapies has presented both a conceptual and a practical challenge in the treatment of patients with advanced non-small cell lung carcinomas (NSCLCs). The relationship of these treatments with specific histologies and predictive biomarkers has made the handling of biopsies the key factor for success. In this study, we highlight the balance between precise histological diagnosis and the practice of conducting multiple predictive assays simultaneously. This can only be achieved where there is a commitment to multidisciplinary working by the tumor board to ensure that a sensible protocol is applied. This proposal for prioritizing samples includes both recent technological advances and the some of the latest discoveries in the molecular classification of NSCLCs (AU)
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Coleções:
06-national
/
ES
Base de dados:
IBECS
Assunto principal:
Adenocarcinoma
/
Biomarcadores Tumorais
/
Carcinoma Pulmonar de Células não Pequenas
/
Neoplasias Pulmonares
Tipo de estudo:
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2013
Tipo de documento:
Article