Alpha lipoic acid efficacy in burning mouth syndrome. A controlled clinical tria
Med. oral patol. oral cir. bucal (Internet)
; 20(4): e435-e440, jul. 2015. tab, ilus
Artigo
em Inglês
| IBECS
| ID: ibc-138970
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
BACKGROUND:
A double-blind placebo-controlled trial was conducted in order to evaluate the efficacy of alpha lipoic acid (ALA) and determine the statistical significance of the outcome variables. Burning mouth syndrome (BMS) is defined as an oral burning sensation in the absence of clinical signs which could justify the syndrome. Recent studies suggest the existence of neurological factors as a possible cause of the disease. MATERIAL ANDMETHODS:
60 patients with BMS, in two groups case group with 600 mg/day and placebo as control group; with follow up of 2 months.RESULTS:
64% of ALA patients reported some level of improvement, with a level of maintenance of 68.75% one month after treatment. 27.6% of the placebo group also demonstrated some reduction in BMS symptoms.CONCLUSIONS:
Long-term evolution and the intensity of symptoms are variables that reduce the probability of improvement with ALA treatmentRESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Síndrome da Ardência Bucal
/
Ácido Tióctico
Tipo de estudo:
Ensaio clínico controlado
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Med. oral patol. oral cir. bucal (Internet)
Ano de publicação:
2015
Tipo de documento:
Artigo
Instituição/País de afiliação:
GAP Toledo/Spain
/
Universidad Complutense de Madrid/Spain