Presence and correlates of apathy in non-demented depressed and non-depressed older persons
Eur. j. psychiatry
; 29(2): 119-130, abr.-jun. 2015. ilus, tab
Artigo
em Inglês
| IBECS
| ID: ibc-141410
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background and Objectives:
Apathy is a behavioral syndrome that often co-occurs with depression. Nonetheless, the etiology of apathy and depression may be different. We hypothesized that apathy occurs more often in depressed compared to non-depressed older persons; and that independent correlates for apathy will be different in depressed and non-depressed older persons.Methods:
In this cross-sectional study of Netherlands Study of Depression in Older Persons (NESDO), a total of 350 depressed older persons according to the Composite International Diagnostic Interview (CIDI) and 126 non-depressed older persons, aged at least 60 years were recruited in several Medical Centres and general practices. In both depressed and non-depressed older persons, those with and without apathy as assessed with the Apathy Scale (score greater than or equal to 14) were compared with regard to socio-demographic, clinical, and biological characteristics.Results:
Apathy was present in 75% of the depressed and 25% of the non- depressed older persons. Independent correlates of apathy in both depressed and non-depressed older persons were male gender and less education. Furthermore, in depressed older persons, higher scores on the Inventory of Depressive Symptomatology (IDS) and, in non-depressed older persons, a higher C-reactive protein (CRP) level correlated independently with apathy.Conclusions:
Apathy occurred frequently among both depressed and non-depressed older persons. Among depressed older persons, apathy appeared to be a symptom of more serious depression, whereas among non-depressed persons apathy was associated with increased CRP being a marker for immune activation, suggesting a different a etiology for apathy in its own right (AU)
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Envelhecimento
/
Demência
/
Depressão
/
Apatia
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Pesquisa qualitativa
/
Fatores de risco
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Eur. j. psychiatry
Ano de publicação:
2015
Tipo de documento:
Artigo
Instituição/País de afiliação:
GGNet Mental Health/The Netherlands
/
Leiden University Medical Center/The Netherlands
/
VU University Medical Center and GGZ ingest/The Netherlands