Recurrent wheezing and asthma after bocavirus bronchiolitis
Allergol. immunopatol
; 44(5): 410-414, sept.-oct. 2016. tab
Artigo
em Inglês
| IBECS
| ID: ibc-155851
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
BACKGROUND:
Human bocavirus (HBoV) was recently discovered and identified as an important cause of respiratory infection in young children. However, the relationship between HBoV-bronchiolitis and the development of recurrent wheezing has not yet been established.OBJECTIVE:
We designed this study in order to describe the mid-term outcome, regarding the development of recurrent wheezing and asthma of HBoV-bronchiolitis patients and to compare it with RSV-bronchiolitis infants.METHODS:
We studied 80 children (10 with HBoV and 70 with RSV infection), currently aged ≥4 years and previously hospitalised during the seasons 2004-2009 due to acute bronchiolitis. Epidemiological and clinical data were collected through structured clinical interviews at the follow-up visit. Spirometry and skin prick tests to common food and inhaled allergens were performed.RESULTS:
All HBoV-patients developed recurrent wheezing and half of them had asthma at age 5-7 years. Almost 30% required hospital admission for recurrent wheezing. Asthma (odds ratio (OR)=1.28) and current asthma (OR=2.18) were significantly more frequent in children with HBoV-bronchiolitis than in RSV-bronchiolitis. FEV1 values were 99.2±4.8 in HBoV-group vs.103±11 in RSV-group, p 0.09. No differences were found with respect to allergic rhinitis, atopic dermatitis, food allergy, proportion of positive prick tests, and family history of atopy or asthma.CONCLUSIONS:
Severe HBoV-bronchiolitis in infancy was strongly associated with asthma at 5-7 yearsRESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Recidiva
/
Asma
/
Bronquiolite
/
Sons Respiratórios
/
Bocavirus Humano
Tipo de estudo:
Estudo prognóstico
/
Pesquisa qualitativa
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Allergol. immunopatol
Ano de publicação:
2016
Tipo de documento:
Artigo
Instituição/País de afiliação:
Hospital Severo Ochoa/Spain
/
Hospital Universitario La Paz/Spain
/
Instituto de Salud Carlos III/Spain