Genomic Plasticity of Vibrio cholerae
Int. microbiol
; 20(3): 138-148, sept. 2017. ilus
Artigo
em Inglês
| IBECS
| ID: ibc-171332
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Vibrio cholerae is one of the deadliest pathogens in the history of humankind. It is the causative agent of cholera, a disease characterized by a profuse and watery diarrhoea that still today causes 95.000 deaths worldwide every year. V. cholerae is a free living marine organism that interacts with and infects a variety of organisms, from amoeba to humans, including insects and crustaceans. The complexity of the lifestyle and ecology of V. cholerae suggests a high genetic and phenotypic plasticity. In this review, we will focus on two peculiar genomic features that enhance genetic plasticity in this bacterium the division of its genome in two different chromosomes and the presence of the superintegron, a gene capture device that acts as a large, low-cost memory of adaptive functions, allowing V. cholerae to adapt rapidly (AU)
RESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Cólera
/
Diarreia
/
Doenças Negligenciadas
Base de dados:
IBECS
Assunto principal:
Vibrio cholerae
/
Cólera
/
Fatores de Iniciação em Procariotos
/
Diarreia
Tipo de estudo:
Estudo de etiologia
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Int. microbiol
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
Universidad Complutense Madrid/Spain
/
Universidad Complutense de Madrid/Spain