Biomarkers in breast cancer: a consensus statement by the Spanish Society of Medical Oncology and the Spanish Society of Pathology
Clin. transl. oncol. (Print)
; 20(7): 815-826, jul. 2018. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-173633
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
This consensus statement revises and updates the recommendations for biomarkers use in the diagnosis and treatment of breast cancer, and is a joint initiative of the Spanish Society of Medical Oncology and the Spanish Society of Pathology. This expert group recommends determining in all cases of breast cancer the histologic grade and the alpha-estrogen receptor (ER), progesterone receptor, Ki-67 and HER2 status, in order to assist prognosis and establish therapeutic options, including hormone therapy, chemotherapy and anti-HER2 therapy. One of the four available genetic prognostic platforms (MammaPrint®, Oncotype DX®, Prosigna® or EndoPredict®) may be used in node-negative ER-positive patients to establish a prognostic category and decide with the patient whether adjuvant treatment may be limited to hormonal therapy. Newer technologies including next-generation sequencing, liquid biopsy, tumour-infiltrating lymphocytes or PD-1 determination are at this point investigational
RESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Neoplasias da Mama
/
Perfilação da Expressão Gênica
Tipo de estudo:
Guia de prática clínica
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Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2018
Tipo de documento:
Artigo
Instituição/País de afiliação:
Doce de Octubre University Hospital/Spain
/
Fundación Jiménez Díaz University Hospital/Spain
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General University Hospital of Alicante/Spain
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Gregorio Marañón University Hospital/Spain
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Hospital Universitario La Princesa/Spain
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Pompeu Fabra University/Spain
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Ramón y Cajal University Hospital/Spain
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University Hospital Complex of Santiago/Spain
/
Virgen del Rocio University Hospital/Spain