Long-term crude probabilities of death among breast cancer patients by age and stage: a population-based survival study in Northeastern Spain (Girona-Tarragona 1985-2004)
Clin. transl. oncol. (Print)
; 20(10): 1252-1260, oct. 2018. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-173712
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background:
We provide population-based long-term survival indicators of breast cancer patients by quantifying the observed survival, and the probabilities of death due to breast cancer and to other causes by age and tumor stage at diagnosis. Methods; We included a total of 10,195 female patients diagnosed before 85 years with invasive primary breast cancer in Girona and Tarragona during the periods 1985-1994 and 1995-2004 and followed-up until December 31st 2014. The survival indicators were estimated at 5, 10, 15 and 20 years of follow-up comparing diagnostic periods.Results:
Comparing diagnostic periods I) the probability of death due to other causes did not change; II) the 20-year survival for women diagnosed ≤ 49 years increased 13% (1995-2004 = 68%; 1985-199455%), whereas their probability of death due to breast cancer decreased at the same pace (1995-2004 = 29%; 1985-1994 = 42%); III) at 10 years of follow-up, decreases in the probabilities of death due to breast cancer across age groups switched from 11 to 17% resulting in a risk of death reduction of 19% after adjusting by stage. During 1995-2004, the stage-specific 10-year probabilities of death due to breast cancer switched from 3-6% in stage I, 18-20% in stage II, 34-46% in stage III and surpassed 70% in stage IV beyond 5 years after diagnosis.Conclusions:
In our study, women diagnosed with breast cancer had higher long-term probability to die from breast cancer than from other causes. The improvements in treatment and the lead-time bias in detecting cancer in an early stage resulted in a reduction of 19% in the risk of death between diagnostic periodsRESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Neoplasia da Mama
Base de dados:
IBECS
Assunto principal:
Neoplasias da Mama
/
Estadiamento de Neoplasias
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2018
Tipo de documento:
Artigo
Instituição/País de afiliação:
Fundació Lliga per a la Investigació i Prevenció del Càncer (FUNCA)/Spain
/
Generalitat de Catalunya (GENCAT)/Spain
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Institut d'Investigació Biomèdica Girona Josep Trueta (IDIBGI)/Spain
/
Institut d'Investigació Biomèdica de Girona (IDIBGI)/Spain
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Institut dInvestigació Biomèdica Girona Josep Trueta (IDIBGI)/Spain
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MC MUTUAL/Spain
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St. Jude Childrens Research Hospital/USA
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Universidad de Barcelona/Spain