Changing perspectives in atopic dermatitis
Allergol. immunopatol
; 46(4): 397-412, jul.-ago. 2018. tab
Artigo
em Inglês
| IBECS
| ID: ibc-177873
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Atopic dermatitis (AD) is a multifaceted disease that involves a complex interplay between the skin and the immune system. The course of the disease depends strongly on the genetic background of the patient and on yet poorly-defined environmental factors. Changes in lifestyle could be behind the dramatic rise in the prevalence of AD across continents; including hygienic conditions, food, social habits, skin microbiome or exposure to a number of allergens. Although AD typically develops in childhood and disappears after a few years, in a relatively large number of patients it continues into adulthood. Adult AD can also appear de novo but it is often underdiagnosed and its treatment can be challenging. New, highly effective drugs are being developed to manage moderate and severe forms of the disease in adults. In this review, we highlight the most recent developments in diagnostic tools, current insights into the mechanistic basis of this disease, and therapeutic innovations
RESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Dermatite Atópica
Limite:
Humanos
Idioma:
Inglês
Revista:
Allergol. immunopatol
Ano de publicação:
2018
Tipo de documento:
Artigo
Instituição/País de afiliação:
Hospital 12 Octubre/Spain
/
Hospital Clínic and Universitat de Barcelona/Spain
/
Hospital General Universitario de Alicante/Spain
/
Hospital Son Espases/Spain
/
Hospital de Basurto/Spain
/
Universidad Autónoma de Barcelona/Spain
/
Universidad Autónoma de Madrid/Spain
/
University of Cadiz/Spain