Problemas clínicos en micología médica: problema número 54 / Clinical problems in medical mycology: problem number 54

RESUMEN

No disponible

ABSTRACT

A 26 year_old woman, who had been submmited to a classic cholecystectomy for a lithic cholecystitis, was admitted in the Hepathology Unit of the F. J. Muniz Hospital of Buenos Aires City, due to persistent jaundice, weight loss, asthenia, arterial hypotension, ascites and periumbilical ulcer. These skin lesions were located under an adhesive tape which was around a Kehr tube. Laboratory studies showed anemia, hyperbilirrubinemia, increased level of hepatic enzymes and a positive anti-mitochondrial antibodies test 1/80. The diagnosis of her liver disease was autoimmune hepatitis and the patient received corticosteroid treatment by oral route. The microbiological study of the skin lesions showed hyaline, wide, non_septate hyphae in the microscopic study, and Rhizopus arrhizus was isolated in cultures. Colloidal dispersion of amphotericin B at a daily dose of 5 mg/kg intravenously was administered and a surgical debridement of the cutaneous lesions was done. Skin lesions improved with this treatment, but her hepatic condition turned worse and evolved to a fatal hepatic insufficiency. She could not receive a liver transplant due to the lack of a compatible donor