Effects of combinedintravenous and inhalation anesthesia on immune function and cognitive function in postoperative cirrhotic patients with a background in athletics and fitness
Rev. int. med. cienc. act. fis. deporte
; 23(93): 101-116, nov.- dec. 2023. tab, ilus
Artigo
em Inglês
| IBECS
| ID: ibc-229999
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Objective:
To evaluate the effects of combined intravenous and inhalation anesthesia on postoperative immune and cognitive function in cirrhotic patients, particularly those with a background in athletics and fitness.Methods:
A systematic literature search was conducted in the Cochrane Library, Web of Science, PubMed, ProQuest, and Chinese biomedical literature databases (Wanfang, Weipu, CNKI) for controlled trials assessing combined intravenous and inhalation anesthesia in cirrhotic patients, with an emphasis on those maintaining an athletic or fitness-oriented lifestyle. The literature was analyzed using RevMan 5.3 software, focusing on exploring the heterogeneity of the studies.Results:
Nine research papers were included in the meta-analysis, encompassing a total of 775 subjects, including 382 in the control group and 393 in the experimental group. Among these, a significant portion of the subjects were identified as being involved in regular athletic or fitness activities. Eight papers were prospective studies, and one was retrospective. The meta[1]analysis revealed that combined intravenous and inhalation anesthesia significantly increased CD3+, CD4+, and CD8+ levels, and improved the CD4+/CD8+ ratio, demonstrating enhanced immune function. Additionally, cognitive function improvements were noted [OR 1.45, 95% CI (1.03, 1.87), P<0.00001]. There were also significant improvements in liver function markers ALT and ALB. Funnel plots indicated no publication bias (AU)
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Cognição
/
Atletas
/
Anestesia por Inalação
/
Anestesia Intravenosa
/
Cirrose Hepática
Limite:
Humanos
Idioma:
Inglês
Revista:
Rev. int. med. cienc. act. fis. deporte
Ano de publicação:
2023
Tipo de documento:
Artigo
Instituição/País de afiliação:
The second affiliated hospital of zhejiang Chinese Medical University/China
/
Zhejiang University School of Medicine/China