The efficacy and safety of ketamine for depression in patients with cancer: A systematic review / La eficacia y seguridad de la ketamina para la depresión en pacientes con cáncer: una revisión sistemática
Int. j. clin. health psychol. (Internet)
; 24(1): [100428], Ene-Mar, 2024. ilus, tab
Artigo
em Inglês
| IBECS
| ID: ibc-230370
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Background:
Management of depression in the oncology population includes supportive psychotherapeutic interventions with or without psychotropic medication, which take time to demonstrate effectiveness. Fast-acting interventions, like ketamine, can provide a rapid antidepressant effect; however, there has been limited research on effects of ketamine among cancer patients. The objective of this review is to provide an overview of research on the efficacy and safety of ketamine on depression in patients with cancer.Methods:
We reviewed the published literature in MEDLINE® (via PubMed®), EMBASE, and Scopus from 1 January 1982 to 20 October 2022. We screened the retrieved abstracts against inclusion criteria and conducted a full‐text review of eligible studies. Following extraction of data from included studies, we used a framework analysis approach to summarize the evidence on using ketamine in patients with cancer.Results:
All 5 included studies were randomized clinical trials conducted in inpatient settings in China. In all included studies ketamine was administered intravenously. Three studies used only racemic ketamine, and two studies used both S-ketamine and racemic ketamine. All included studies reported ketamine a tolerable and effective drug to control depression symptoms.Conclusion:
Included studies showed administration of sub-anesthesia ketamine significantly improves postoperative depression among patients with cancer.(AU)
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Pacientes
/
Psicologia Clínica
/
Depressão
/
Ketamina
/
Neoplasias
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Int. j. clin. health psychol. (Internet)
Ano de publicação:
2024
Tipo de documento:
Artigo
Instituição/País de afiliação:
Moffitt Cancer Center/United States
/
Tehran University of Medical Sciences/Iran
/
University of Chester/England
/
University of South Florida Morsani/United States
/
University of South Florida/United States