Post-Pandemic Aftermath: A Two-Year Follow-Up of the Effect of COVID-19 on Oncological Outcomes after Radical Prostatectomy for Prostate Cancer
Arch. esp. urol. (Ed. impr.)
; 77(1): 43-48, 28 jan. 2024. tab
Artigo
em Inglês
| IBECS
| ID: ibc-230497
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Purpose:
This study aimed to evaluate the indirect effect of the Coronavirus Disease 2019 (COVID-19) pandemic on the surgical outcomes and oncological results of patients who underwent surgery during the lockdown period.Methods:
We analysed data from 423 patients who underwent radical prostatectomy between 2016 and 2022, with a cut-off date of March 16, 2020. Patients were categorised into two groups, namely, pre-lockdown (n = 289) and during lockdown (n = 134). Perioperative variables, histopathological findings and oncological outcomes, including prostate-specific antigen (PSA) levels and biochemical recurrence (BCR), were assessed.Results:
The number of radical prostatectomy increased by 24.26% during lockdown. The study included patients with a mean follow-up of 21 months. A nonsignificant trend towards a higher PSA level at presentation was found (14.22 vs. 12.53 ng/dL, p = 0.216). The International Society of Urological Pathology grade was not significantly different among radical prostatectomy specimens (p = 0.669). Lymph node involvement increased during the COVID-19 period (p = 0.046). The pT classification in prostatectomy specimens increased during the pandemic, but the difference from the pre-pandemic value was not statistically significant. The BCR rates were 24.6% pre-lockdown and 29.9% during lockdown (p = 0.136).Conclusions:
The COVID-19 pandemic led to poor postoperative results. Through a 2-year follow-up, this research investigated the effect of the pandemic on the oncological outcomes, particularly BCR, of patients who underwent radical prostatectomy. Further extended investigations and multi-institutional studies should be conducted to quantify the effect of the pandemic on various cancer outcomes and inform crisis management strategies (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Neoplasias da Próstata
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Arch. esp. urol. (Ed. impr.)
Ano de publicação:
2024
Tipo de documento:
Artigo
Instituição/País de afiliação:
Cochin Hospital-Port Royal/France
/
Iuliu Hatieganu University of Medicine and Pharmacy/Romania
/
Regional Institute of Gastroenterology and Hepatology Prof. Dr. Octavian Fodor/Romania
/
The Oncology Institute Prof. Dr. Ion Chiricuţă/Romania
/
University of Oradea/Romania