The use of tricyclic antidepressants in the treatment of temporomandibular jointdisorders: Systematic review of the literature of the last 20 years

ABSTRACT

Many therapies have been proposed for the management of temporomandibular disorders, including the use of differentdrugs. However, lack of knowledge about the mechanisms behind the pain associated with this pathology, and the fact thatthe studies carried out so far use highly disparate patient selection criteria, mean that results on the effectiveness of the differentmedications are inconclusive. This study makes a systematic review of the literature published on the use of tricyclicantidepressants for the treatment of temporomandibular disorders, using the SORT criteria (Strength of recommendationtaxonomy) to consider the level of scientific evidence of the different studies. Following analysis of the articles, and infunction of their scientific quality, a type B recommendation is given in favor of the use of tricyclic antidepressants for thetreatment of temporomandibular disorders (AU)