Palatal atypical histiocytic granuloma

ABSTRACT

In this report, we examine a clinical entity called atypical histiocytic granuloma (AHG), which is characterized byulceroproliferative lesions that clinically simulate a squamous cell carcinoma or specific granulomatous lesions.AHG histologically shows a histiocytic proliferation and is characterized by specific mitotic activity, which hasthe potential to be confused with malignant processes of a lymphoid origin. There are few cases reported in theliterature, and an adequateknowledge of the process is required in order to avoid a misdiagnosis, especially as regardsmalignant processes. To our knowledge, a case of this type of lesion in the palate has not yet been described.We present a case of an atypical histiocytic granuloma which occurred in the form of an ulcerated pediculatedlesion in the palatine mucosa (an uncommon localization that not yet has been researched). This case histologicallyshowed a histiocytic infiltration with an increase in the mitotic index, eosinophils and an accumulation ofhaemosiderin. The lesion resolved spontaneously after the biopsy, without recurring after a period of five years.This report stresses the important value of immunohistochemistry in diagnosing the lesion and also discusses thesimilarities and differences between other lesions that may be confused, potentially leading to a misdiagnosis (AU)

RESUMEN

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