Temporal relationship of allergic rhinitis with asthma and other co-morbidities in a Mediterranean country: A retrospective study in a tertiary reference allergy clinic
Allergol. immunopatol
; 38(5): 246-253, sept.-oct. 2010. tab, graf
Article
em En
| IBECS
| ID: ibc-83173
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background: Allergic rhinitis is a global health problem which causes major illness and represents a risk factor for asthma. The primary aim of the study was to record the clinical pattern of allergic rhinitis and its temporal relation with asthma in a Greek population. Methods: Three-hundred and sixteen subjects with documented diagnosis of allergic rhinitis in a two-year period were included in this study. All participants completed a standardised questionnaire with full retrospective epidemiological data for rhinitis; in addition, serum IgE measurement and skin prick tests with 22 common inhalant allergens were carried out, while spirometry was performed in subjects with self-reported or doctor-diagnosed asthma. All subjects with at least one positive skin test were included in study analysis. Results: One-hundred and sixty five out of 316 patients (49.1%) stated self reported-asthma while in 63/316 (19.9%) asthma was documented with spirometry. One hundred out of 165 (60.6%) had rhinitis as first clinical manifestation while in 24/165 (14.5%) asthma symptoms appeared first; the remaining 31/165 (24.9%) reported simultaneous onset of upper and lower airways' symptoms. About 68.5% were sensitised to seasonal allergens exclusively, while 50% were sensitised to ≥1 of Parietaria, grasses sp., Olea eur. The duration of rhinitis in the subpopulation of patients with self-reported asthma (n=165) was significantly higher compared with non-asthmatics (mean=3.22 years, p<0.001). Survival analysis for the estimation of asthma onset showed that the mean time interval with rhinitis only is 16.6 years (median 12 years, incidence 0.0596). Conclusions: The unique environmental conditions and the aerobiology of each area clearly affect the clinical features of respiratory allergy
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Coleções:
06-national
/
ES
Base de dados:
IBECS
Assunto principal:
Hipersensibilidade Respiratória
/
Asma
/
Rinite Alérgica Sazonal
Tipo de estudo:
Observational_studies
Limite:
Humans
Idioma:
En
Revista:
Allergol. immunopatol
Ano de publicação:
2010
Tipo de documento:
Article