The prevalence of aspirin-induced asthma in Saudian asthmatic patients
Allergol. immunopatol
; 38(4): 181-186, jul.-ago. 2010. tab
Artigo
em Inglês
| IBECS
| ID: ibc-86414
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background:
Aspirin-induced asthma (AIA), is a distinct clinical syndrome affecting some asthmatic patients. Although the name of the condition relates to aspirin, it is well established that affected patients are cross-sensitive to all non-steroidal anti-inflammatory drugs (NSAIDs).Objectives:
Assessing the prevalence of AIA among Saudian asthmatic patients.Methods:
This is a retrospective study of the medical records of asthmatic patients.Results:
The prevalence of AIA in the patients studied was found to be 12.6%. Statistical analyses indicated that AIA was associated with more severe asthma [odds ratio (OR) (95% Confidence interval (CI)) in Group I cases 2.86 (1.24 to 6.59) respectively (p<0.05)]. The results showed that some allergic conditions were significantly more common in Group I for allergic rhinitis (OR=2.19, 95% CI 0.895.37, p<0.05), pollinosis (OR=1.59, 95% CI 0.852.98, p<0.05) for antibiotic allergy (OR=1.25, 95% CI 0.652.41, p<0.05) and for atopic dermatitis (OR=1.34, 95% CI 0.702.55, p<0.05). Family history of allergy had a more significant role in Group I cases (OR=1.27, 95% CI 0.682.37, p<0.05). No gender difference on asthma severity was detected in either group (Chi2=2.19, p>0.05).Conclusion:
The prevalence of respiratory symptoms triggered by aspirin/NSAID use was 12.6% in the asthmatics studied. AIA appears to be a significant problem and further investigations of the mechanisms of these responses and the possible link between this syndrome and other allergic co-morbidities are requiredRESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
/
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Objetivo 9: Redução de doenças não transmissíveis
/
Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
Base de dados:
IBECS
Assunto principal:
Asma
/
Comorbidade
/
Aspirina
/
Rinite Alérgica Sazonal
/
Dermatite Atópica
/
Hipersensibilidade Alimentar
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo de prevalência
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Allergol. immunopatol
Ano de publicação:
2010
Tipo de documento:
Artigo
Instituição/País de afiliação:
Cairo University/Egypt