Spasmogenic non-cholinergic activity of a digestive gland homogenate of the amphibian snail Pomacea lineata spix 1827

RESUMO

The digestive gland of Pomacea lineata, a prosobranch gastropod mollusc inhabiting both fresh water and land, does not contain cholinomimetic compounds as do the glands species of Aplysia, marine opisthobranch gastropods, in which both acetylcholine and urocanylcholine are present. The only pharmacological detected for the digestive fland of Pomacea was spasmogenic activity of a crude homognate containing 0.1 g tissue equivalents on the snail's own esophagus bathed in 10ml of a physiological prepared on the basis of the animnal's hemolymphy composition. The spamodic activity was not blocked by atropine, bromlysergic acid diethylamide or anthazoline