Perspectives on clinical trials for hypertonic saline/dextran solutions for the treatment of traumatic shock
Braz. j. med. biol. res
; 22(2): 291-3, 1989. tab
Artigo
em Inglês
| LILACS
| ID: lil-105568
Biblioteca responsável:
BR1.1
RESUMO
Animal studies with hypertonic solutins suggest that they can achieve resuscitation of hypovolemic shock with extremely small volumes. Such small volume ressuscitation might be ideal in the field treatment of injured patients. Our studies to date, with 60 patients enterd into a prospective, randomized, placebo-controlled, and double-blind clinical trial, suggest that the use of a 7.5% NaCl/Dextran 70 solution increases blood pressures during transport. The solutions have been safe, and we have encoutered no adverse side effects from their use. Survival rates to date favor use of the solutions, but we do not have convincing statistical significance yet in that regard
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Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Ressuscitação
/
Choque Traumático
/
Hidratação
Tipo de estudo:
Ensaio clínico controlado
/
Estudo observacional
Limite:
Humanos
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1989
Tipo de documento:
Artigo
/
Congresso e conferência