La anemia de la glomerulonefritis aguda post-estreptocócica / Anemia associated to acute post streptococcal glomerulonephritis
Rev. méd. Chile
; 122(11): 1276-82, nov. 1994. tab, ilus
Article
em Es
| LILACS
| ID: lil-144026
Biblioteca responsável:
CL1.1
ABSTRACT
Thirty-three children with post-streptococcal acute glomerulonephritis, age x8.3 years (range 6-12) were studied prospectively. Mean initial hematocrit (Hct) was 31.6 percent with 90 percent showing Hct under the normal lower limit for this age group. Reticulocyte index (RI) was <0.5 in half of the cases. Serum iron concentration, total iron binding capacity (TIBC) and percentaje of transferrin saturation were normal for this age group although 75 percent of the children had increased serum ferritin levels. At the time of discharge, Hct increased to 35.1 percent but 44 percent still had anemia. Hct increased spontaneously for 105 days stabilizing at 38 percent. Based on Hct changes, 3 groups were defined Group I (3 individuals) normal upon discharge; Group II (19) partial recovery at discharge, slow recovery stabilizing after 105 days; Group III (11) lower Hct, slower recovery but with RI significantly higher than group II (0.96 vs 0.45 p<0.01). Our data suggest that although hemodilution is present in all, it may be considered the solely factor only in 3 cases (Group I). In group II, evidence of bone marrow depression was indicated by the low RI. On the other hand, the intense anemia that could not be justified only by hemodilution and marrow depression in group II, suggest other pathogenic factors
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Infecções Estreptocócicas
/
Glomerulonefrite
/
Anemia
Tipo de estudo:
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
1994
Tipo de documento:
Article
País de publicação:
Chile