The role of apoptosis in the inhibition of a secondary tumor by concomitant resistance in a mouse model of metastases
Medicina (B.Aires)
; 56(4): 393-6, 1996. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-186262
Biblioteca responsável:
BR1.1
ABSTRACT
Resistance of tumor-bearing mice to a second tumor challenge, that is, concomitant resistance, was studied using the LB tumor model. In a secondary LB tumor implant inhibited by concomitant resistance an increase in the percentage of apoptotic cells and alterations in cell cycle distribution were observed. Similar alterations were observed in LB tumor cells incubated with serum from tumor-bearing mice. The data presented in this paper suggest that apoptosis is one of the mechanisms involved in tumor dormancy due to concomitant resistance.
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Base de dados:
LILACS
Assunto principal:
Apoptose
/
Linfoma
/
Metástase Neoplásica
Limite:
Animais
Idioma:
Inglês
Revista:
Medicina (B.Aires)
Assunto da revista:
Medicina
Ano de publicação:
1996
Tipo de documento:
Artigo