Diagnóstico de la neurocisticercosis humana mediante ELISA-IgG usando un antígeno purificado / Diagnosis of human neurocysticercosis by ELISA-IgG using a purified antigen
Bol. chil. parasitol
; 51(3/4): 85-90, jul.-dic. 1996. tab, graf
Artigo
em Espanhol
| LILACS
| ID: lil-189295
Biblioteca responsável:
CL1.1
ABSTRACT
An analysis of inmunodiagnosis data for human neurocysticercosis (NC) by ELISA-IgG, complement fixation (CSF) from confirmed cases of different hospitals from the metrolitan area of Santiago, Chile, was performed. The cut-off value was determined by using serum samples from 60 apparently healthy persons, whose absorbance values were the mean plus three standard desviations. The sensitivity of ELISA was 97,0 percent and 100 percent for serum samples and CSF respectively. This assay was considered od statistical significance (p< 0,05) when it was compared with CFT. Specificity was stablished by testing a purified antigen over 109 different helminthiasis serum samples, 185 neurological affections other than NC and 60 control samples. A 98,3 percent of global specificity was found. The use of ELISA-IgG and a purified antigen in the approach of inmune diagnosis of NC is considered a useful assay, particularly if it is perfomed on paired serum/CSF samples.
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Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Helmintíase
/
Doenças Negligenciadas
/
Zoonoses
Base de dados:
LILACS
Assunto principal:
Técnicas In Vitro
/
Imunoglobulina G
/
Cisticercose
/
Ensaio de Imunoadsorção Enzimática
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Idioma:
Espanhol
Revista:
Bol. chil. parasitol
Assunto da revista:
ALIMENTOS
/
Parasitologia
Ano de publicação:
1996
Tipo de documento:
Artigo