Leucemia mieloide aguda MO: características clínicas y de laboratorio / Acute myeloid leukemia MO: clinical and laboratory features
Rev. méd. Chile
; 125(4): 433-7, abr. 1997. tab, ilus
Article
em Es
| LILACS
| ID: lil-196287
Biblioteca responsável:
CL1.1
RESUMO
Patients and methods:
Eight patients, our of 368, with acute myeloid leukemia that were studied in the Hematology Laboratory of a public hospital in Santiago, were classified as LMA-MO.Results:
Blast cell morphology was undifferentiated or of subtype FAB-L2 lymphoblastic leukemia with medium sized blasts, agranular basophilic cytoplasm, reticular nuclear chromatin and a prominent nucleolus. Cytochemical staining was negative for peroxidase and esterases, immunophenotyping showed the expression of one or more myeloid antigens (CD13, CD33) and was negative for lymphoid antigens. Immunocytochemical expression of myeloperoxidase was positive in the three cases where it was performed. Only one patient achieved complete remission and is free of disease after 36 months of follow up. All other patients died without obtaining remission, six shortly after the onser and one 12 months after.Conclusions:
The diagnosis of LMA-MO is essential considering its dismal prognosis
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Leucemia Mieloide
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
Es
Revista:
Rev Med Chil
/
Rev. méd. Chile
/
Rev. méd. Chile (En línea)
/
Revista médica de Chile
Assunto da revista:
MEDICINA
Ano de publicação:
1997
Tipo de documento:
Article
País de publicação:
Chile