Genetic diversity and differentiation in natural Plasmodium falciparum populations inferred by molecular typing of the merozoite surface proteins 1 and 2
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;35(5): 527-530, Sept.-Oct. 2002. tab, graf
Article
em En
| LILACS
| ID: lil-328007
Biblioteca responsável:
BR1.1
ABSTRACT
Genetic diversity and differentiation, inferred by typing the polymorphic genes coding for the merozoite surface proteins 1 (Msp-1) and 2 (Msp-2), were compared for 345 isolates belonging to seven Plasmodium falciparum populations from three continents. Both loci yielded similar estimates of genetic diversity for each population, but rather different patterns of between-population differentiation, suggesting that natural selection on these loci, rather than the transmission dynamics of P. falciparum, determines the variation in allele frequencies among populations
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Plasmodium falciparum
/
Variação Genética
/
Proteínas de Protozoários
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Proteína 1 de Superfície de Merozoito
/
Antígenos de Protozoários
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil