The sesquiterpene lactone dehydroleucodine reversibly inhibits Allium cepa L. root growth
Biocell
; 25(1): 29-34, Apr. 2001.
Artigo
em Inglês
| LILACS
| ID: lil-335887
Biblioteca responsável:
BR1.1
RESUMO
Here, we prove that dehydroleucodine, a sesquiterpene lactone, at low concentrations (25-100 microM) slowed down the Allium cepa L root growth by 22-70 respectively neither affecting cell viability nor cell size. Removal of the drug after 24 h incubation restored the normal growth rate of the roots. Higher concentrations (200 microM) of dehydroleucodine were deleterious for the roots. As cell size did not change, it is most likely that dehydroleucodine affected some event of cell division cycle making it longer. Thus, dehydroleucodine could be a useful tool to slow down cell proliferation.
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Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Sesquiterpenos
/
Raízes de Plantas
/
Cebolas
/
Lactonas
Idioma:
Inglês
Revista:
Biocell
Assunto da revista:
Clulas
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Argentina
Instituição/País de afiliação:
Universidad Nacional de Cuyo/AR
/
Universidad Nacional de San Luis/AR