Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
Mem. Inst. Oswaldo Cruz
; 102(1): 121-123, Feb. 2007. tab
Artigo
em Inglês
| LILACS
| ID: lil-440640
Biblioteca responsável:
BR1.1
ABSTRACT
To investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM anti-HAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6 percent (95 percent CI 72.7-78.3), ranging from 55.4 to 97.3 percent, depending on the communities studied. The prevalence of anti-HAV increased significantly with age, from 13.8 percent in the age 0-5 age group to 96.6 percent in those older than 40 years. The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future HAV vaccination programs.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Vírus da Hepatite A
/
Anticorpos Anti-Hepatite A
/
População Negra
/
Hepatite A
Tipo de estudo:
Estudo diagnóstico
/
Estudo de prevalência
/
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Idoso
/
Idoso, 80 anos ou mais
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2007
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Fundação Oswaldo Cruz/BR
/
Instituto de Patologia Tropical e Saúde Pública/BR
/
Universidade Federal de Goiás/BR
/
Universidade Federal de Mato Grosso do Sul/BR