Farmacovigilancia en nosocomios de la ciudad de Córdoba. Dos años de experiencia del Departamento de Farmacología como efector periférico de ANMAT / Drug monitoring in hospitals of Cordoba City (Argentina). 2-year-experience of the Pharmacological Department as a peripheric effect of ANMAT

RESUMEN

Se diseñó un estudio de Farmacovigilancia (FVG), centrado en tres Hospitales Públicos de Córdoba, buscando detectar Reacciones Adversas por medicamentos. A tal fin se realizaron cursos formadores de recursos humanos en FVG. Se distribuyeron fichas de FVG., de diseño propio, recuperadas luego. Para cálculo estadístico se aplicó el INFO 4. Se recuperaron 84 fichas informadas Los grupos de medicamentos involucrados fueron Antibióticos (22%), cardiovasculares (16%), antiulcerosos (10%), ansiolíticos (8.75%), AINEs (8%), oncológicos (6%), anticonvulsivantes (3.75%), hipolipemiantes (3.5%), hormonas sexuales (2.5%), hipoglucemiantes (2.5%), expansores plasmáticos (2.5%). Los órganos afectados por RAM fueron SNC (25%), piel (25%), gastrointestinal (17.5%), Sangre (7.5%), cardiovascular (7.5%), respiratorio (7%), inmunes (6%), renal (4%). El análisis de imputabilidad indicó RAM Definidas 10% - RAM Probables 90%.

ABSTRACT

There were designed Monitorings study (FVG), centred on three Public Hospitals of C6rdoba, seeking to detect Adverse Reactions for medicines. To such purpose there were realized forming courses of human resources in FVG. FVG's cards were distributed, of own design, recovered then. For statistical calculation there was applied the INFO 4. 84 informed cards were recovered. The groups of involved medicines they were Antibiotics (22%), cardiovascular (16%), antiulcerous (10%), anxiolytics (8.75%), nonsteroidal anti-inflammatory (8%), onchologics (6%), anticonvulsants (3.75%), hypolypemics (3.5%), sexual hormones (2.5%), hypoglycemics (2.5%), plasmatic expansors (2.5%). The organs affected by RAM were Central Nervous System (25%), skin (25%), gastrointestinal (17.5%), Bleeds (7.5%), cardiovascular (7.5%), respiratory (7%), immune (6%), renal (4%). The analysis of imputability indicated Definite RAM 10 % Probable RAM 90%.