Prenatal alcohol exposure did not affect impulsivity in rats that performed delay or probability discounting tasks
Psychol. neurosci. (Impr.)
; 4(1): 123-130, Jan.-June 2011. graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-604541
Biblioteca responsável:
BR85.1
ABSTRACT
Individuals who fall under the spectrum of the Fetal Alcohol Syndrome have a higher prevalence of several cognitive disturbances, including a greater probability of being diagnosed with attention-deficit hyperactivity disorder (ADHD). Some of these effects, such as hyperactivity and attentional impairments, are already well established in the literature. The assessment of impulsive choice, however, has received little attention in human and animal studies. In the present study, we attempted to investigate the effects of prenatal ethanol exposure on two tasks related to impulsive choice that have never been studied in this condition delay and probability discounting. METHOD:
Rats prenatally exposed to ethanol (liquid diets with 0 percent, 10 percent, or 35 percent ethanol-derived calories [EDC] or laboratory chow) were trained to respond for food in either delay (n = 21) or probability (n = 48) discounting tasks performed in computer-controlled operant conditioning chambers.RESULTS:
Prenatal treatment failed to differentiate the rates at which the rats chose the larger reinforcer associated with delay - in a task in which 35 percent EDC was not tested - or risk, although the results suggest that further tests are warranted.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Transtornos Cognitivos
/
Transtornos do Espectro Alcoólico Fetal
/
Comportamento Impulsivo
Tipo de estudo:
Fatores de risco
Limite:
Animais
Idioma:
Inglês
Revista:
Psychol. neurosci. (Impr.)
Assunto da revista:
Neurologia
/
Psicologia
Ano de publicação:
2011
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
Reino Unido
Instituição/País de afiliação:
King's College London/GB
/
Universidade Federal do Rio Grande do Sul/BR